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Vaccines have never been safe and effective: A century of documented failures of smallpox vaccination

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In 1802, a statement was put to the UK House of Commons that vaccination was “entirely safe” and granted “lifelong immunity.”  That statement has been revised over time, but it has never been formally retracted.

Roman Bystrianyk has collected evidence and testimonies regarding early smallpox mass vaccination campaigns, beginning in 1799 and spanning more than a century, proving that the “safe and effective” mantra has always been a lie.

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Traitors to the Royal Vaccinating State

By Roman Bystrianyk, 21 September 2026

Table of Contents

Introduction

The above photograph is of Miss Fannie Lent, of Cincinnati, Ohio. She was vaccinated when a child, and thereafter became a mass of running sores. She visited Zion City a few years ago, and has since died. She suffered the tortures of hell, and was a sight that would melt a heart of stone. “Vaccination,” Leaves of Healing, vol. XXXV, no. 14, 2 January 1915, p. 313.

In 1796, Edward Jenner tested a popular belief: that cowpox protected against smallpox. He obtained cowpox material from a milkmaid and used it to inoculate an eight-year-old boy named James Phipps, whom he then deliberately exposed to smallpox. Because the boy did not fall ill, Jenner concluded that the procedure – cowpoxing, later given the more scientific-sounding and mysterious name vaccination (from vacca, Latin for cow) – was effective and conferred lifelong protection. On 17 March 1802, he informed the House of Commons that vaccination was entirely safe, granted lifelong immunity and would rid the world of smallpox.[5]

From the outset, however, many regarded this new notion – built on eighty years of smallpox inoculation – as anything but safe or effective. Yet the idea took hold almost immediately. As Dr. William Rowley, MD, observed in 1805 – less than a decade since vaccination had started – “Whoever had not taken the oaths of supremacy and allegiance to vaccination, or who dared to doubt the infallibility of Cow-pox inoculation even in its infancy, even before any judgment could be formed, were ignominiously treated as traitors to the royal vaccinating state, as rebellious subjects to the Jennerian despotic power.”[6] Decades later, Dr. Charles Creighton likewise noted how firmly this idea had taken root: by 1801, he wrote, professors and others of his class “on the Continent as well as in England were already deeply committed“ and that “anyone who undertakes to answer for Jenner and his theories, must shatter his own reputation for scientific and historical knowledge.”[7]

What follows is not a history of vaccination’s triumphs but a record of its failures – drawn almost entirely from the testimony of physicians who witnessed them firsthand. The timeline that unfolds across the following decades chronicles smallpox vaccination’s inability to shield against the very disease it promised to conquer, together with the injuries and deaths that followed in its trail. The quotations assembled here, spanning 1799 to 1910, call into question the triumphant narrative so widely accepted about this medical intervention.

1799

In 1799, Dr. Drake, a surgeon from Stroud, England, undertook an experiment to assess Jenner’s new preventive measure, using vaccine material obtained directly from Edward Jenner. The children were subsequently challenged with a smallpox inoculation to determine whether the cowpox procedure had conferred protection. The so-called protection failed.

1801

Dr. Charles Creighton, writing in 1890, described how a professor at Göttingen confronted forty-five cases of smallpox among forty-nine recently vaccinated children – and still refused to abandon the practice (emphasis added):

1804

By 1804, Goldson of Portsea had already published cases of smallpox occurring “within two or three years of vaccination.”[10]

1805

Dr. William Rowley, MD, Physician to Her Majesty’s Lying-in Hospital, published ‘Cow-pox inoculation NO SECURITY against Small-pox infection’, documenting numerous instances in which vaccinated children contracted smallpox despite the confident claims of invulnerability made by those administering the vaccinations.

1806

Dr. Squirrel of the Small-pox Hospital, St. Pancras, observed in 1806 that the public had become so alarmed by post-vaccinal smallpox that they rejected both inoculation methods altogether. As he reported (emphasis added):

1809

In 1809, Brown of Musselburgh recorded 48 cases of children who had caught small-pox “within three, four, five, six, seven, eight, nine, and ten years of their vaccination.” Brown was compelled to conclude “that vaccination even in the most perfect form is not only incapable of imparting permanent security against small-pox, but even of retaining the system in that state of impregnation capable of only allowing it to exercise its influence to a safe or trifling extent.”[15]

Also, in 1809 the Medical Observer reported a series of patients demonstrating the failure of natural cowpox or vaccination to protect against smallpox:

1810

Charles Maclean, MD, published an extensive work, ‘On the State of Vaccination in 1810’, examining the shortcomings of vaccination. Within its pages, he meticulously presented tables filled with names of people, accompanied by references, which revealed a staggering 535 cases of smallpox emerging after cowpox inoculation. Additionally, the records indicated 150 fatalities resulting from either smallpox or adverse reactions to cowpox after cowpox vaccination.[17]

1817

In 1817, a medical journal acknowledged what practitioners had been reluctant to state publicly – that smallpox was appearing “alarmingly” often in patients who had been vaccinated by “the most skilful practitioners” (emphasis added):

1818

In 1818 Dr. Monro of Edinburgh published numerous cases observed by himself and others in which smallpox in its perfect form succeeded to vaccination in its perfect form. Smallpox remained epidemic in Scotland, attacking many hundreds of the vaccinated to varying degrees.[21]

In 1818 Thomas Brown, a surgeon with 30 years of experience in Musselburgh, Scotland, recounted how no one in the medical profession “could outstrip me in zeal for promoting vaccine practice.” But after vaccinating 1,200 people and discovering that many still contracted and even died from smallpox, his conscience could no longer support vaccination.

1820

Dr. Thomson published a book in 1820 on the varioloid type of the disease. In 1819, nineteen, and in 1825, 147 vaccinated persons were admitted with smallpox into the London Small-Pox Hospital.[23]

By 1820, only two decades after Jenner’s promise of lifelong immunity, a medical journal reported that post-vaccinal smallpox had become so ordinary that it “no longer excited any interest” – including seven vaccinated children in one family, all stricken (emphasis added):

1828

The theory that ascribed to vaccination the reduction of smallpox in the earlier years of the century, in some places to the point of extinction, received a rude shock when in 1828 a severe epidemic broke out at Marseilles and 2,000 vaccinated persons caught the disease.[25]

1829

Writing in The Lancet in 1829, Mr. Fosbroke recalled the epidemic of 1820-1822, which not only reached Dr. Jenner’s own household but “fell upon great numbers” of the vaccinated (emphasis added):

In 1829 William Cobbett, a farmer, journalist and English pamphleteer, wrote about the failure of vaccination to protect people from smallpox.

1836 to 1851

Mr. Marson records 3,094 cases of post-vaccinal small-pox treated by him at the Highgate Hospital between 1836 and 1851, and a further series of 10,661 such cases between the years 1852 and 1867.[28]

1842

In 1842 Thomas Brown of Musselburgh, Surgeon, published ‘An Investigation of the present Unsatisfactory and Defective State of Vaccination’ (emphasis added):

1843

Dr. Gregory, who gives a table showing the number and mortality from small-pox in the well-vaccinated population of Copenhagen from 1824 to 1835, reports that of 3,839 persons attacked by small-pox, no fewer than 3,093 had been vaccinated. It was these figures that led Dr. Gregory, the physician to the Small-Pox Hospital, in 1843, to declare “that some material error had crept into the views originally entertained regarding the power and capabilities of the vaccine inoculation. If small-pox can invade so large a proportion of a well-vaccinated population, it is obvious that all idea of banishing that disease from the earth is vain and illusory.”[30]

1850

A letter to a newspaper in 1850 asserted there were more admissions to the London Small-Pox Hospital in 1844 than during the smallpox epidemic of 1781 before vaccination began (emphasis added):

1854

In 1854, The Morning Chronicle reported cases of “small-pox confluent, unmodified” in patients bearing the scars of successful vaccination – and, in the same column, two infant deaths following vaccination:

1869

Writing in 1869, as vaccinated children continued to die of smallpox and revaccination was being urged with increasing frequency, Dr. William Job Collins asked how often the “disgusting and unnatural practice” must be repeated – and whether the whole scheme should not be denounced as “a farce and a sham”:

1870 to 1883

Dr. Gayton, during the years 1870 to 1883, treated 8,234 cases of smallpox in vaccinated persons in the hospitals of the Metropolitan Asylums Board.[34]

1879

By 1879, with vaccination enforced by Act of Parliament, Dr. William Hycheman argued that smallpox had increased in both extent and frequency since the law took hold – and, drawing a direct parallel between the two diseases, catalogued the fatal injuries he had found in the bodies of vaccinated children (emphasis added):

1882

Writing in the National Board of Health Bulletin in 1882, a physician warned that vaccine matter distributed by the New England Vaccine Company had produced severe reactions in nearly every person vaccinated (emphasis added):

1887 to 1888

Dr. Gayton at Sheffield in 1887 to 1888: 5,035 vaccinated persons were treated for smallpox.[37]

1888

In 1888, a physician who had avoided vaccination since childhood decided to be revaccinated “to make himself doubly sure against danger” – and died of blood poisoning sixteen days later (emphasis added):

1898

In 1898, Dr. Wilder observed that during the 1871–1872 pandemic, the vaccinated often contracted severe smallpox more rapidly than the nonvaccinated (emphasis added):

1902

In 1902, the Pacific Coast Journal of Homoeopathy reported the case of a five-year-old girl who, though in “thoroughly good health before the vaccination,” died twenty days later of a generalised bullous eruption (emphasis added):

1903

In 1903, Professor Robert Alexander Gunn, MD, New York Medical College, New York, testified as follows:

1910

By 1910, with vaccination required for school attendance despite parental protest, Physical Culture published one reader’s catalogue of the injuries she had witnessed – including a fatal case and a young woman left permanently disfigured (emphasis added):

Conclusion

The record assembled here spans more than a century, yet its testimony is remarkably consistent. From Dr. Drake’s three children in 1799 to Professor Gunn’s 1903 testimony and the parents’ accounts of 1910, the same pattern recurs: patients vaccinated according to the most approved methods contracted smallpox anyway, often in its most severe and confluent forms, and sometimes died. The same physicians who once championed vaccination – Thomas Brown of Musselburgh, who vaccinated 1,200 people before his conscience turned; Dr. Gregory of the Small-Pox Hospital, who was forced to admit that the “idea of banishing that disease from the earth is vain and illusory” – became its most credible critics precisely because they had once believed.

Equally consistent is the response of the vaccination establishment. Failures were attributed to unskilful operators, stale lymph or spurious matter – never to the theory itself. As Cobbett observed of the Ringwood outbreak, in which more than a hundred vaccinated persons died, “the failure was imputed to unskilful operators; to the staleness of the matter; to its not being of genuine quality.” When the evidence could no longer be explained away, it was suppressed: Maclean noted that “very few deaths from cow-pox appear in the Bills of Mortality, owing to the means which have been used to suppress knowledge of them,” while Rowley described how dissenters were “ignominiously treated as traitors to the royal vaccinating state.” Dr. Stokes, who was revaccinated to “make himself doubly sure against danger,” died of blood poisoning within sixteen days.

By the early twentieth century, the statistical picture was damning. Dr. Gayton treated 8,234 cases of smallpox in vaccinated persons between 1870 and 1883, and another 5,035 at Sheffield in 1887–88. Marson recorded 3,094 post-vaccinal cases at Highgate between 1836 and 1851, and 10,661 more between 1852 and 1867. Gregory found that of 3,839 smallpox patients in well-vaccinated Copenhagen, 3,093 had been vaccinated. These were not isolated failures but the routine experience of the institutions established to treat the disease.

Yet the promise made to the House of Commons in 1802 – that vaccination was “entirely safe,” and granted “lifelong immunity” – was never formally retracted. Instead, it was revised: protection was said to wane, revaccination became necessary, and injuries and deaths went ignored. Dr. William Job Collins saw the revision for what it was, asking in 1869 how often the “disgusting and unnatural practice” must be repeated before the whole scheme was exposed as “a farce and a sham” – one that “would have died a natural death, had it not been for the legislative interference and the vested interests at stake.” The quotations gathered here suggest that this retreat was not a scientific correction but a strategic one – an inherited obligation, as Creighton put it, “of hard swearing to successive generations.”

The timeline ends in 1910, but the debate it records did not. The questions these physicians raised – whether vaccination actually protected, whether it might in fact increase the disease it claimed to prevent, whether its risks outweighed its benefits, and whether its advocates had suppressed evidence to the contrary – would simply fade into the whispers of the past. What remains is the documentary record: a century of medical testimony, largely forgotten, from those who saw the failures with their own eyes – and refused to look away.

Sources and resources

  • [1] William Job Collins, MD, Have You Been Vaccinated, and what Protection is it Against the Small Pox? 1869, London, p. 24.
  • [2] George William Winterburn, PhD, MD, The Value of Vaccination: A Non-partisan Review of Its History and Results, 1886, pp. 42–43.
  • [3] “John Le Gay Bereton, Esq., MD, MRCS, LAC,” New South Wales, Compulsory Vaccination, Presented to the Parliament by Command, September 20, 1881, Sydney: Thomas Richards, Government Printer, pp. 1043–1046.
  • [4] Vaccination Tracts. Letters and Opinions of Medical Men, 1892, Province: Snow & Farnham, p. 14.
  • [5] John Baron, The Life of Edward Jenner, pp. 490–491.
  • [6] William Rowley, MD, Cow-pox inoculation NO SECURITY against Small-pox infection, 1805, London, printed by J. Barfield, sold by J. Harris, pp. 26–27.
  • [7] Dr. Charles Creighton, MD, “Vaccination: A Scientific Inquiry,” The Arena, September 1890, vol. 2, no. 4, pp. 436–437.
  • [8] Charles Creighton, Jenner and Vaccination, 1889, pp. 95–96.
  • [9] Dr. Charles Creighton, MD, “Vaccination: A Scientific Inquiry,” The Arena, September 1890, vol. 2, no. 4, pp. 436–437.
  • [10] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [11] William Rowley, MD, Cow-pox inoculation NO SECURITY against Small-pox infection, 1805, Printed by J. Barfield, sold by J. Harris, London, p. viii.
  • [12] William Rowley, MD, Cow-pox inoculation NO SECURITY against Small-pox infection, 1805, Printed by J. Barfield, sold by J. Harris, London, p. 13.
  • [13] William Rowley, MD, Cow-pox inoculation NO SECURITY against Small-pox infection, 1805, London, printed by J. Barfield, sold by J. Harris, pp. 26–27.
  • [14] William Job Collins, Have You Been Vaccinated And what Protection is it Against the Small Pox? An Essay, 1868, p. 44.
  • [15] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [16] William Scott Tebb, MD, A Century of Vaccination and What It Teaches, 1898, Swan Sonnenschein & Co., London, p. 126.
  • [17] Charles Maclean, MD, On the State of Vaccination in 1810, London, Sherwood, Neely, and Jones; [and] C. Birnie, pp. 82–92, 95–97.
  • [18] Charles Maclean, MD, On the State of Vaccination in 1810, London, Sherwood, Neely, and Jones; [and] C. Birnie, London, p. 101.
  • [19] Charles Maclean, MD, On the State of Vaccination in 1810, Sherwood, Neely, and Jones; [and] C. Birnie, London, p. 103.
  • [20] “Observations on Prevailing Diseases,” The London Medical Repository Monthly Journal and Review, vol. VIII, July–December 1817, p. 95.
  • [21] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [22] Thomas Brown, Surgeon Musselburgh, “On the Present State of Vaccination,” The Edinburgh Medical and Surgical Journal, vol. 15, 1819, p. 67.
  • [23] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [24] The Monthly Gazette of Health, vol. V, no. 51, March 1, 1820, p. 439.
  • [25] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [26] “Observations by Mr. Fosbroke,” The Lancet, vol. II, 1829, p. 583.
  • [27] William Cobbett, Advice to Young Men and (Incidentally) to Young Women, W Cobbet, London, 1829, pp. 224–225.
  • [28] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 172.
  • [29] Thomas Brown of Musselburgh, Surgeon, An Investigation of the present Unsatisfactory and Defective State of Vaccination, 1842, pp. 136–137.
  • [30] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 171.
  • [31] “Small Pox and Vaccination,” Hampshire Telegraph & Sussex Chronicle, March 2, 1850.
  • [32] The Morning Chronicle, April 12, 1854.
  • [33] William Job Collins, MD, Have You Been Vaccinated, and what Protection is it Against the Small Pox? 1869, London, p. 32.
  • [34] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 172.
  • [35] William Hycheman, MD, “Small-pox and Vaccination,” The Medical Tribune, February 15, 1879, vol. I, no. 4, pp. 172–175.
  • [36] “Spurious Vaccination,” National Board of Health Bulletin, vol. 3, no. 36, March 4, 1882, Washington, D.C., p. 334.
  • [37] Final report of the Royal Commission appointed to inquire into the subject of vaccination, London: Printed for Her Majesty’s Stationery Office, by Eyre and Spottiswoode, 1896, p. 172.
  • [38] “A Physician Killed by Vaccination,” Journal of Hygeio-therapy, September 1888, vol. II, no. 9, p. 203.
  • [39] Alexander Wilder, MD, “The Fallacy of Vaccination,” The Metaphysical Magazine, vol. III, no. 2, May 1898, p. 88.
  • [40] “Vaccination Followed by Acute Fatal Pemphigus,” Pacific Coast Journal of Homoeopathy, April 1902, p. 111.
  • [41] Order to Show Cause. N. Y. SUPREME COURT, KINGS COUNTY, In the Matter of The Application of Edmund C. Viemeister for a Peremptory Writ of Mandamus, Patrick J. White, President of the Board of Education, and F. H. Meade, Principal of Public School No. 12. Borough of Queens Supreme Court: Appellate Division-Second Department, 1903, pp. 5–10.
  • [42] “The Horrible Results of Vaccination,” Physical Culture, vol. XXIII, No. 6, June, 1910, p. 618.

Featured image: Edward Jenner (1749-1823) performing his first vaccination against smallpox on James Phipps, a boy of eight, on 14 May 1796. Source: Getty Images

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Rhoda Wilson
While previously it was a hobby culminating in writing articles for Wikipedia (until things made a drastic and undeniable turn in 2020) and a few books for private consumption, since March 2020 I have become a full-time researcher and writer in reaction to the global takeover that came into full view with the introduction of covid-19. For most of my life, I have tried to raise awareness that a small group of people planned to take over the world for their own benefit. There was no way I was going to sit back quietly and simply let them do it once they made their final move.
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